Publications

Cover Features

Recent Representative Publications

1. Guo D, Chen Y, Wu Y, Cheng J, Lin Y, Lai W, Ma W, Yang H, Han L, Ma L, Jia H, Liu X. Multi-omics characterization of the skin microbiota reveals the anti-aging roles of Stenotrophomonas maltophilia. Microbiome. 2026 Jun 3. 

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2. Meng D, Ding H, Deng Q, Li X, Tao Y, Liu X. Protocol for generating human tonsil immune organoids with epithelial and germinal center layers using low-Matrigel culture. STAR Protoc. 2026 Mar 20;7(1):104381. 

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3. Hussain S, Ayoub M, Ye F, Liu X. MLN2SVG: domain-aware spatially variable gene detection using contrastive variational autoencoder and multi-level neighbor search. Brief Bioinform. 2026 May 4;27(3):bbag210. doi: 10.1093/bib/bbag210. PMID: 42080589; PMCID: PMC13137336.

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4. Huang Y, Zhou Q, Gui M, Guo D, Cheng J, Ma W, Shu P, Liu X. Dynamic multi-omics mechanisms underpinning retinol tolerance: stage-specific reconstruction of skin barrier function and host-microbiome metabolic interactions. Front Microbiol. 2025 Oct 27;16:1668712.

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5. Yixuan Huang;  Yang Xiao; Alexander Teng;  Fei Ye;  Yiyao Yu; Chenyi Lei; Ruihao Zhang; Zhangyang Gao; Cheng Tan;Xiao Liu. Text-To-AMP: Antimicrobial Peptide Design Guided by Natural Text. 2025. IEEE

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6. Ye F, Chen M, Huang Y, Zhang R, Li X, Wang X, Han S, Ma L, Liu X. LightCTL: lightweight contrastive TCR-pMHC specificity learning with context-aware prompt. Brief Bioinform. 2025 May 1;26(3):bbaf246.

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7. Xia JJ, Zhong Q, Li ZM, Wei QZ, Jiang LY, Duan C, Jia HJ, Tan YM, Han LY, Krutmann J, Wang J, Liu X. Culture dependent and independent approaches reveal the role of specific bacteria in human skin aging. IMetaOmics. 2024 Sep 10;1(2):e26. 

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8. Yang Xiao; Yueshan Huang; Yu Zhao; Fan Xu; Qin Ren; Bing He;  Jianhua Yao;  Xiao Liu. Multimodal-AIR-BERT: A Multimodal Pre-trained Model for Antigen Specificity Prediction in Adaptive Immune Receptors. 2024. IEEE

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1. Zhiming Li#, Jingjing Xia#, … Xiao Liu*, Jiucun Wang*. Characterization of the human skin resistome and identification of two microbiota cutotypes. Microbiome. 2021. (IF 11.6, JCR Q1)

 

2. Xiaomin Liu#, Hanshi Xu#, … Xiao Liu*, Shilong Zhong*. New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin. The Pharmacogenomics Journal. 2021

 

3.Jinghua Wu#, Xie Wang, …Changgang Li*, Xiao Liu*.Developing an Unbiased Multiplex PCR System to Enrich the TRB Repertoire Toward Accurate Detection in Leukemia. Frontiers in Immunology. 2020

 

 

4.Xu Jiang#, Shiyu Wang#, … Xiao Liu*, Xuan Zhang*. Comprehensive TCR repertoire analysis of CD4 T-cell subsets in rheumatoid arthritis. Journal of Autoimmunity. 2020.(Correspondence, IF 7.5, JCR Q1)


 

 

5.  Gang Yi#, Yi Zhao#,… Xiao Liu*, Bin Li*. Single-cell RNA-seq unveils critical regulators of human FOXP3+ regulatory T cell stability. Science Bulletin. 2020.(Correspondence, IF 6.3, JCR Q1)

 

 

6.Xiao Liu#, Wei Zhang#, Ming Zhao#, et al., T cell receptor β repertoires as novel diagnostic markers for systemic lupus erythematosus and rheumatoid arthritis. Annals of the Rheumatic Diseases. 2019. (IF 14.3, JCR Q1)

 

 

7.Kai Gao#, Lingyan Chen#, …, Xiao Liu* and Xiu Qiu*. Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire. Frontiers in Immunology. 2019.(IF 4.7, JCR Q1)

 

8.Ke Cao#, Jinghua Wu#,…Shaoheng he*, Xiao Liu*. T cell receptor repertoire data provides new evidence for hygiene hypothesis of allergic diseases. Allergy. 2019. (IF 6.8, JCR Q1)

 

 

9.Wei Zhang#, Longlong Wang#, …Xiao Liu*. PIRD: Pan Immune Repertoire Database. Bioinformatics. 2019. (IF 4.5, JCR Q1)

 

 

 

10.Yi Zhao, Xiao Li,…Yong Hou* and Xiao Liu*. Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood. GigaScience. 2019. (IF 4.7, JCR Q1)

 

 

11.Wei Zhang, Xinyue Li, Longlong Wang,…I-Ming Wang* and Xiao Liu*. Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires. The Journal of Immunology. 2019. (IF 4.7, JCR Q1)

 

12.Mingdao Wang, Yan Li, …, Xiao Liu*. Alterations in the human gut microbiome associated with Helicobacter pylori infection. FEBS Open Bio. 2019 (IF 2, JCR Q2)

13.Chen Huang, Xuemei Li, Jinghua Wu,…Xiao Liu*. The landscape and diagnostic potential of T and B cell repertoire in Immunoglobulin A Nephropathy. Journal of Autoimmunity. 2018 (IF 7.5, JCR Q1)

 

 

14. Longlong Wang, Wei Zhang, Liya Lin,…Xiao Liu*. A comprehensive analysis of the T and B lymphocytes repertoire shaped by HIV vaccines. Frontiers in Immunology. Sept. 2018. (IF 5.5, JCR Q1)

 

15. Xiao Liu*, Jinghua Wu. History, Applications and challenges of immune repertoire research. Cell Biology and Toxicology. Jan 2018. (IF 5.1, JCR Q1)


 


16. Wei Zhang, Qiang Feng, Changxi Wang, … Christian Datz* and Xiao Liu*, Characterization of BCR repertoire in the intestinal mucosa and of tumor-infiltrating lymphocytes in colorectal adenoma and carcinoma. The Journal of Immunology. March 2017. (Cover article)


 


17.Ting Wang, Changxi Wang, Jinghua Wu,…, Xiao Liu*. The different T-cell receptor repertoires in breast cancer tumors, draining lymph nodes, and adjacent tissues. Cancer Immunology Research. December 2016. DOI: 10.1158/2326-6066.CIR-16-0107 (IF 8.6, JCR Q1)


 

 


18. Wei Zhang, I-ming Wang, Changxi Wang,…, Xiao Liu*. IMPre: an accurate and efficient software for prediction of T- and B-cell receptor germline genes and alleles from rearranged repertoire data. Frontiers in Immunology. doi: 10.3389/fimmu.2016.00457 (IF 6.0, JCR Q1)


 

 

 


19.Ling-Hao Zhao#, Xiao Liu#, He-Xin Yan# et al., Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nature Communications, 2016 Oct 5;7:12992. doi: 10.1038/ncomms12992 (IF 11.9, JCR Q1)


 


20.Jinghua Wu, Shan Jia, Changxi Wang,…, Xiao Liu*. Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing. Frontiers in Immunology. 04 October 2016 | http://dx.doi.org/10.3389/fimmu.2016.00403 (IF 6.0, JCR Q1)


 

 


21.Longfei Fu, Xinyang Li, Wei Zhang,..Xiao Liu*. A comprehensive profiling of T- and B-lymphocyte receptor repertoires from a Chinese-origin rhesus macaque by high-throughput sequencing. PLoS ONE. 12(8):e0182733 · August 2017 


 

 

 


22.Zheng Su, Junjie Zhang, Chanchal Kumar,…, Xiao Liu*. Species specific exome probes reveal new insights in positively selected genes in nonhuman primates. Scientific Reports. 2016 Sep 23;6:33876. doi: 10.1038/srep33876.